

This clinical trial is open to adults who:
• Are 18 years or older• Have been diagnosed with advanced solid tumors including Breast, Ovarian, Pancreatic, Uterine or Liver cancer• Have cancer that has spread (metastatic) • Have tried other treatments that are no longer controlling the cancer• Both men and women are welcome to participate.
Are You Eligible?

• You will gain access to a new treatment that is not available anywhere else. In fact, ERX-315 can only be given to patients in this clinical trial.• You may benefit from this new treatment• You will receive care from a specialized team of cancer doctors• You will be helping advance research that may benefit others in the future.
Why should I join a clinical trial?

with Advanced Solid Tumors

• The Kinghorn Cancer Center• Cancer Research SAContact: Kelly Mead.+61 (8) 8359 2565 / admin@crsa.au• MQ Health Medical Oncology and Clinical Trials at Macquarie University.Contact: Luke Wood.+61 (2) 9812 2956 / clinicaltrials@mq.edu.au

• Two visits per week for one-hour IV treatments
• Regular check-ups to monitor your progress
Comprehensive Support
• Detailed explanation of everything before you decide
• Time to discuss with family and your regular doctor
• 24/7 access to your study team for questions or concerns
You Have Control
• You can leave the study at any time, for any reason
• No pressure - the decision is entirely yours

A: This is the first human trial, which means you'd be among the first to potentially benefit from this innovative approach. Early safety testing has shown only mild changes in blood tests.
Q: What types of cancer is ERX-315 being tested for?
A: It is intended for advanced metastatic solid tumors that have failed one or more therapies including breast, ovarian, pancreatic, endometrial, and liver cancers.
Q: How long will treatment last?
A: Treatment continues as long as you're benefiting and feeling well. You control the timeline.
Q: Do I need to be in Australia to participate in the ERX-315 clinical trial?
A: Yes. The only sites currently recruiting are in Australia: The Kinghorn Cancer Center and MQ Health in Sydney and Cancer Research SA in Adelaide. You will need to go to one of these locations for treatment and tests.
Q: What about side effects?
A: As with any new treatment, side effects are possible. Our team monitors you closely, and you'll receive immediate care for any concerns at no cost to you.
Q: Will ERX-315 work for me?
A: We do not know if this treatment will work for you. The mechanism of action of ERX-315 is different from conventional cancer treatments. The only way to see if ERX-315 works for you is to participate in the clinical trial.
• Talk to your oncologist - they can help determine if this trial suits your situation
• Ask questions - we encourage you to learn everything you want to know
• Take your time - there's no rush to decide
For complete eligibility details: visit ClinicalTrials.gov

For U.S. patients: A similar trial may open in America by 2026. Stay connected with your oncology team for updates.


• The Kinghorn Cancer Center• Cancer Research SAContact: Kelly Mead.+61 (8) 8359 2565 / admin@crsa.au• MQ Health Medical Oncology and Clinical Trials at Macquarie University.Contact: Luke Wood.+61 (2) 9812 2956 / clinicaltrials@mq.edu.au
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