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In July 2022, our founders discovered how our breakthrough therapies worked by targeting a fundamental vulnerability in cancer cells, killing cancer cells while leaving normal cells intact. Instantly, our paper became one of the most downloaded articles published by prestigious Nature Cancer. journal. Today we are approved to start our Phase I clinical trials with drugs developed from this groundbreaking discovery.

Our therapies work by shutting down protein synthesis in cancer cells, causing catastrophic levels of endoplasmic reticulum stress that lead the cell to death by apoptosis, or programmed cell death. Our first therapy heralds a series of innovations in cancer therapy:

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The first therapy to induce sustained and uncompensated endoplasmic reticulum stress causing cell death.

The first targeted agent against LIPA’s role in the endoplasmic reticulum.

The only oral agent with cytotoxic activity against most forms of breast cancer (ER+, ER-, TNBC), and other untreatable cancers including; Ovarian, Pancreatic, Liver and Endometrial.


*These statements are based on preclinical research and have not been evaluated in clinical trials nor by the FDA or any government health agency.

A new hope for patients with metastatic therapy resistant cancers.

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Where to find us

Dallas Office:
3033 Irving Blvd,
Dallas. TX. 75247

Mailing Address:
3060 Pegasus Park Dr.
Dallas. TX. 75247

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Inclusion criteria:
  • Patients must be at least 18 years of age at the time of signing the informed consent.
  • Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1.
  • Patients must have histologically or cytologically confirmed solid tumor, primarily including but not limited to breast, ovarian, pancreatic, endometrial, and hepatocellular carcinoma, that is advanced unresectable and/or metastatic disease for whom standard therapies do not exist or are no longer effective
  • Patients must have measurable disease as per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.
  • Adequate baseline organ function and hematologic function
  • Life expectancy >3 months
Exclusion criteria
  • Systemic anti-cancer therapy within 4 weeks of first dose of study drug
  • Major surgery (as defined by the Investigator) within 4 weeks of first dose of study drug.
  • Uncontrolled intercurrent illnesses
  • Known history of LIPA deficiency, such as Wolman disease or Cholesterol ester storage disease.